Buffalo Bills Visit (7-2) Indianapolis Colts (4-5) Week 10 on Sunday. Kickoff at Lucas Oil Stadium is scheduled for 1pm ET (CBS). Let’s analyze BetMGM Sportsbook’s NFL odds Bills and Colts possibilitiesand make our expert NFL picks and predictions.

QB Josh Allen He led the Bills to a 4-game winning streak. Buffalo has scored at least 30 points in three straight games, including a key 30-27 victory over the Miami Dolphins, to extend its AFC East lead.

Coming off a 21-13 loss to the Minnesota Vikings on Thursday Night Football, the Colts face their third straight team with a winning record and look to keep their losing streak from reaching three. Indianapolis will continue on its way Joe Flacco 2023 first round pick under center Anthony Richardson to try to keep up and earn a trip to the postseason.

However, both clubs will need to continue this struggle without at least one top-level pass-catching weapon. How will this affect betting?

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Bills on Colts odds

Provided by BetMGM Sports Betting; access USA TODAY Sports Scores and Sports Betting Odds hub For full list NFL odds. Lines last updated at 9:49 AM ET.

• Money Line (ML): Bills -210 (Bet $210 to win $100) | Colts +170 (Bet $100 to win $170)
• Anti-proliferation (ATS): Bill -4 (-110) | Colts +4 (-110)
• Over/Under (O/U): 46.5 (O: -110 | U: -110)

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Notable injuries for Bills at Colts

Invoice nickname

• W.R. Keon Coleman (wrist) out
• W.R. Amari Cooper (wrist) doubtful

Colts’ nickname

• W.R. Michael Pittman (back, finger) out

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Bills at Colts picks and predictions

Guess

Bills 30, Colts 27

money line

Bills’ ML juice isn’t too expensive on the road, but it’s still too inconvenient to get excited about.

Having Flacco under center justifies a spread bet against the Colts. But I’m having trouble arguing why I should remove Bills directly.

TO GO PAST.

against the spread

Buffalo is just 5-4 ATS. Vegas appears to have pinned Indianapolis; The Colts sit at 7-2 ATS.

More importantly, Indianapolis finished 3 of the 4 games in which Flacco had significant performances this season; but lost to Minnesota last week.

I recommend Bills faders take this route instead of going directly up.

BET LIMITS +4 (-110).

Top/Bottom

The absence of Pittman and Coleman (potentially Cooper as well) will rightly keep bettors away from a strong total of 46.5. Additionally, the Colts are 3-6 overall, including the Unders’ 4-game winning streak, compared to Buffalo’s 5-4 record.

However, both attacks proved versatile enough to find help among secondary weapons. W.R. Josh Downs He connected well with Flacco and could turn to Bills TE Dalton Kincaid and R.B. ray davis Assisting in the passing game to help Allen and RB James Cook.

I’d like to see the energy in the Over drop to a more positive number closer to kick-off, but I’m still confident in the current line if you need action soon. Allen should keep the scoreboard active by playing indoors with his pass rush and dual-threat game.

BET OVER 46.5 (-110).

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