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Invisible to the naked eye: 15 amazing images taken under the microscope
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Invisible to the naked eye: 15 amazing images taken under the microscope

A groundbreaking image mouse Brain tumor cells were awarded 2024 Nikon Small World Competition. At first glance, the image seen below may look like a science fiction plant structure, but it is actually the actin, microtubules, and nucleus of the cells. “This image reveals how disruptions in the cell’s cytoskeleton (the structural framework and ‘highways’ known as microtubules) can lead to diseases such as Alzheimer’s and ALS.” press release explains.

Image, Dr. With the help of Eric Vitriol, Dr. Shot by Bruno Cisterna. Capturing the image required a lot of patience for research scientists at Augusta University. “I spent about three months perfecting the staining process to ensure the cells were clearly visible,” Cisterna said. “After waiting five days for the cells to differentiate, I needed to find the right field of view where differentiated and undifferentiated cells interact. This took about three hours of precise observation under the microscope to capture the right moment, which involved many tries, and countless hours of study to get it right.”

Differentiated mouse brain tumor cells
1st row. Differentiated mouse brain tumor cells (actin, microtubules and nuclei). Contributors: Dr. Bruno Cisterna and Dr. Eric Vitriol / Nikon It’s a Small World

The Nikon Small World Competition celebrates its 50th anniversary in 2024, with more than 2,100 entries submitted from 80 countries. Organizers call the awards “the premier forum for recognizing artistry, competence and photographic excellence in photomicrography.”

(Click on the images to expand their beauty.)

two drops into a mushroom-like structure
11th Row. Slime mold on a rotten branch with water droplets. Contributors: Dr. Ferenc Halmos / Nikon It’s a Small World
face of a small two-spotted ladybug
Honorable Mention. Autofluorescence on the face of a small two-spotted ladybug (Diomus Notecens). Credits: Angus Rae / Nikon It’s a Small World
neon shrimp
Honorable Mention. Pickled shrimp. Credits: Christopher Algar / Nikon It’s a Small World
many bubbles that look like faces
Honorable Mention. Cross-section of the rachis (stem) of the fern (Pteridium aquilinum). Contributors: Dr. David Maitland / Nikon Small World David Maitland
cluster of about 25 oval-shaped translucent eggs in a cluster
5th Row. Cluster of octopus (Octopus hummelincki) eggs. Credits: Thomas Barlow and Connor Gibbons / Nikon It’s a Small World
An electric arc between a pin and a wire appears in blue and purple
2nd row. An electric arc between a pin and a wire. Credit: Dr. Marcel Clemens / Nikon Small World
Cross section of European beach grass
Row 7. Cross-section of a European seaside grass (Ammophila arenaria) leaf. Credits: Gerhard Vlcek / Nikon It’s a Small World
Cribraria cancellata, also known as Dictydium cancellatum, slime mold from Finland, microscope image
6th row. Cribraria cancellata, also known as Dictydium cancellatum, slime mold from Finland. Credits: Henri Koskinen / Nikon It’s a Small World
multi-part seed
19th Row. Seed of the Silene plant. Credits: Alison Pollack / Nikon It’s a Small World Alison K. Pollack
Two daphnia (Daphnia sp.) with embryos (left) and eggs (right).
16th Row. Two daphnia (Daphnia sp.) with embryos (left) and eggs (right). Credits: Marek Miś / Nikon It’s a Small World
eight black eyes bulge in a slimy green surface
13th Row. Eyes of the green crab spider (Diaea dorsata). Credits: Paweł Błachowicz / Nikon It’s a Small World
ladybug on leaf
The Image of Separation. Ladybug (Coccinellidae) on a clover (Trifolium repens). Credit: Dr. Marko Pende / Nikon Small World
Fruiting body of Prototrichia metallica, highly nivicolous slime mold. Focus stacked composite of 337 exposures at 10x life size. Eldorado National Forest, Sierra Nevada, Alpine County, California, USA.
The Image of Separation. Fruiting body of Prototrichia metallica, highly nivicolous slime mold. Credits: Timothy Boomer / Nikon It’s a Small World Timothy Boomer
Front part of palm bug
The Image of Separation. Front part of palm tree beetle. Credit: Dr. Sherif Abdallah Ahmed / Nikon It’s a Small World