The frontman of a Welsh rock band says his future is uncertain after his rare, aggressive cancer returned.

The Alarm’s Mike Peters appealed to people to become potential stem cell donors.

Peters, who had to cancel a US tour earlier this year because of his rapidly growing lymphoma, went well in September after receiving experimental therapy at the Christie NHS Foundation Trust in Manchester.

However, the 65-year-old actor announced his return last month.

Peters, who supports U2 and Status Quo on tour, was first diagnosed with chronic lymphocytic leukemia (CLL) 29 years ago, when he was 36.

Earlier this year, doctors diagnosed him with Richter syndrome, in which CLL develops into a much more aggressive lymphoma.

He is currently on a chemotherapy regimen with the aim of starting CAR-T therapy, a complex and specialized type of immunotherapy.

In 2006, Peters founded the Love Hope Power Foundation with his 57-year-old wife, Jules. The couple has two sons, aged 17 and 20.

It has launched a new campaign called One in a Million to double the number of people signing up as potential stem cell donors, which has already encouraged 250,000 people to sign up.

“Exactly 29 years after I was first told of my illness, I now had to prepare for a stem cell transplant,” Peters said.

“Unfortunately, Richter syndrome has aggressively disrupted my hard-earned recovery and denied me the opportunity to have this potentially life-saving procedure.”

She added: “The future is uncertain, but I still have many options and in managing these I want to make sure I help other blood cancer patients like me.”

His partner Jules added: “Whilst this latest setback is a devastating blow to our family, it gives us more time to find the best life-saving match for Mike.”

Michael Gallagher, from blood cancer charity DKMS, which works in partnership with the trust, added: “Currently only 60% of patients will find a matching stem cell donor, making the need for new donors critical.

“We want to help people with blood cancer get a stem cell transplant and have the best possible chance for a healthier future.”